WebJul 8, 2024 · A global registry assessing use of GLP-1 receptor agonists and SGLT2 inhibitors as second-line therapies among patients with type 2 diabetes, DISCOVER was designed with the intent of developing a greater understanding of not only the prevalence, but also factors associated with use of these therapies in a large, prospective database. WebOct 22, 2024 · The guidelines were metformin, then GLP-1, and then SGLT-2, whereas a lot of our colleagues still use a lot of DPP-4s [dipeptidyl peptidase 4] because they’re easy to use. But they don’t have cardiac benefits. They don’t have weight loss that a GLP-1 has. And the cardiac issues. Basically it’s metformin, GLP-1, SGLT-2, would be the ...
Oral and Injectable Diabetes Medications ADA
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DISCOVER Details Gradual Uptake, Need for Improvement in …
WebOct 12, 2024 · Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can reduce CV risk in patients with T2D, and both are recommended by the American Diabetes Association to reduce the risk of major cardiovascular events (MACE). http://mdedge.ma1.medscape.com/internalmedicine/article/203896/cardiology/costs-and-benefits-sglt2-inhibitors-glp-1-ras/page/0/1 WebJul 9, 2024 · Oral semaglutide is the first oral GLP-1 receptor agonist available. SGLT2 inhibitors and GLP-1 receptor agonists are used in patients with type 2 diabetes as … how much water to give cannabis seedling