WebIn humans, both GADL1 and CSAD are expressed in the brain and neurons whereas only CSAD was found in the liver. In mice, both enzymes are expressed in the brain, olfactory bulbs, and skeletal muscle but only CSAD was found in the kidney and liver. GADL1 is named ADC, CSADC, HuADC, HuCSADC in some papers. Structure [ edit] WebOct 10, 2006 · The GDL1 cells were treated with MMC at doses of 0.025, 0.05, and 0.1 microg/mL for 24h and mutations were detected by Spi- and 6-thioguanine (6-TG) selections. The MFs of the MMC-treated cells increased up to 3.4-fold with Spi- selection and 3.5-fold with 6-TG selection compared to MFs of untreated cells. In the Spi- mutants, the number …
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