WebCLINICAL PHARMACOLOGY: Pharmacodynamics: Pilocarpine is a cholinergic parasympathomimetic agent exerting a broad spectrum of pharmacologic effects with predominant muscarinic action. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric, pancreatic, and intestinal … WebJan 25, 1999 · Administration of 5-mg pilocarpine tablets 4 times daily (20 mg/d) was well tolerated and produced significant improvement in symptoms of dry mouth and dry eyes …
Sjögren
Webafter 4 days.10 The PCF advises that in drug induced dry mouth, 5mg four times daily is generally an effective dose.10 Dose adjustments Doses of oral pilocarpine should be reduced in patients with moderate to severe hepatic impairment. Licensed information suggests that the starting dose of pilocarpine should WebFor dry eye and dry mouth, doctors may prescribe pilocarpine hydrochloride or cevimeline, both of which stimulate the lacrimal glands to produce more tears and the salivary glands to create more saliva. Both medications are taken by mouth three times a day. After about two weeks, people usually start to feel some relief. gamecube icon png
Neurogenic Keratoconjunctivitis Sicca
WebJan 21, 2024 · Older adults experiencing drug-induced dry mouth, dry mouth secondary to Sjögren’s syndrome or another systemic disease and dry mouth secondary to radiation treatment for head and neck cancer. … WebJan 25, 1999 · All postdose saliva collections in the 5-mg pilocarpine group were statistically significantly (P≤.003) greater at all points (30, 60, and 90 minutes after dosing) throughout the study. The 60-minute postdose collections (P≤.001) are plotted. WebJun 23, 2024 · Pilocarpine affects the nervous system and increases saliva secretion in the mouth. Pilocarpine is used to treat dry mouth caused by Sjogren's syndrome, or by radiation to treat head and neck cancer. gamecube hyperkin hdmi